Dosing Recommendations Prophylaxisb
Children Adults 75 mg once daily ≤ 15 kg
30 mg once daily
> 15-23 kg
45 mg once daily
> 23-40 kg
60 mg once daily
> 40 kg
75 mg once daily
For prophylaxis of infants < 24 mo of age: 9-23 mo: 3.5 mg/kg once daily 3-8 mo: 3 mg/kg once daily NOT routinely recommended for infants < 3 mo of age due to limited data in this age group
Children ≥ 5 y and Adults 2 inhalations (10 mg total per dose), once daily for 10 days
Adamantane-Based Drugs (not currently used due to resistance) 1-9 y
9-12 y Same as treatment dose
Same as treatment dose
Same as treatment dose
1-9 y 5 mg/kg once daily, not to exceed 150 mgc
≥ 10 y
200 mg/day, either as a single daily dose or div bid
200 mg/day, either as a single daily dose or div bid
b In children for whom prophylaxis is indicated, antiviral drugs should be continued for the duration of known influenza activity in the community because of the potential for repeated and unknown exposures, or until immunity can be achieved aſter immunization.
c FDA approved for prophylaxis down to 12 mo of age. 17
