Contraindications
Active liver disease Arterial bleeding
Clinical Trial Results None completed
Active liver disease Arterial bleeding Pregnant or nursing women or those desiring to be pregnant
None completed
Active liver disease Pregnant or nursing women or those desiring to be pregnant
Active or chronic liver disease Pregnancy, lactation or desire to become pregnant
None completed
Significant dose-related reductions in systolic blood pressure (SBP), diastolic blood pressure (DBP) and LDL-C
standard doses of atorvastatin and simvastatin (The Advicor Versus Other Cholesterol-Modulating Agents Trial
of niacin extended release and simvastatin vs simvastatin monotherapy in patients with increased non-HDL of niacin extended-release and simvastatin with simvastatin 80 mg monotherapy: the SEACOAST II (high-dose) olesterolemic patients. Curr Med Res Opin. 2006;22(10):2041-2053.
