Diagnosis and Assessment of Disease Management of Vaccine Reactions
Are nature and timing of reaction consistent with anaphylaxis? (Note 1) or
Is there a history of possible anaphylaxis to previous doses of this or other vaccines or foods, specifically gelatin, egg, chicken or yeast?
YES
NO
Skin test with vaccine and components (Note 2)
Administer vaccine unless reaction is a contraindication,
eg, encephalopathy aſter pertussis vaccine
+
Additional doses needed? (Note 3) – give graded doses and prepare to treat anaphylaxis (Note 4)
–
Additional doses
needed? (Note 3) – give full vaccine and observe for ≥ 30 mins
2
(continued)
