Figure 2. Anaphylaxis
Epinephrine 1:1000
Adult: 0.2-0.5 mL (mg) Child: 0.01 mL (mg)/kg
Airway/Oxygen Antihistamine
Diphenhydramine IM or slow IV Adult: 25 to 50 mg Child: 1 mg/kg up to 50 mg OR Hydroxyzine IM Adult: 25-100 mg Child: 0.25 mg/kg OR Chlorpheniramine 10-20 mg IV
2nd Line Intravenous fluids Corticosteroids IV/IM
Slow IV (hydrocortisone equivalent) Adult: 100–300 mg Child: ≤ 1 year, 25 mg 1-5 years, 50 mg 6-12 years, 100 mg
OR Dexamethasone Adult: 0.5-20 mg Child 0.2-0.5 mg/kg
Asthma-like Symptoms Nebulized β-agonist Hypotension (adult doses) Dobutamine
IV – 2.5 to 20 mcg/kg/min Norepinephrine
IV – 8-12 mcg/min OR Dopamine
IV – 0.5-2 mcg/kg/min Phenylephrine
IV – 0.1 to 0.5 mg OR 0.1 to 0.18 mg/min
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