Management
26
Table 7. Systemic Antibiotic Therapy for Gonococcal and
Chlamydial Conjunctivitis
Cause Drug of Choice (Dosage)
Adults
Gonococcus
a
Ceriaxone
b
(250 mg IM, single dose) and Azithromycin (1 g
orally, single dose) OR Doxycycline (100 mg orally, twice a day for
7 days)
For cephalosporin-allergic patients: Azithromycin
c
(2 g orally, single
dose)
Chlamydia
d
Azithromycin (1 g orally, single dose ) OR
Doxycycline (100 mg orally twice a day for 7 days)
Children
e
(<18 years)
Gonococcus
Children who
weigh <45 kg
Ceriaxone (125 mg IM, single dose) OR
Spectinomycin
f
(40 mg/kg (maximum dose 2 g ) IM, single dose)
Children who
weigh ≥45 kg
Same treatment as adults
Chlamydia
Children who
weigh <45 kg
Erythromycin base or ethylsuccinate (50 mg/kg/day orally divided
into 4 doses daily for 14 days)
Children who
weigh ≥45 kg
but are aged
<8 years
Azithromycin (1 g orally, single dose)
Children
≥8 years
Azithromycin (1 g orally, single dose) OR
Doxycycline (100 mg orally, twice daily for 7 days)
Neonates
Ophthalmia
neonatorum caused
by N. gonorrhoeae
Ceriaxone (25–50 mg/kg intravenous or IM, single dose, not to
exceed 125 mg )
Chlamydia Erythromycin base or ethylsuccinate (50 mg/kg/day orally divided
into four doses daily for 14 days
g
)
