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Conjunctivitis

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1 Î Conjunctivitis has been cited as one of the most frequent causes of patient self-referral. Conjunctivitis infrequently causes permanent visual loss or structural damage, but the economic impact of the disease in terms of lost work time, cost of medical visits, diagnostic testing, and medication is considerable. Î Chronic and/or recalcitrant conjunctivitis may be indicative of an underlying malignancy, such as sebaceous or squamous cell carcinoma. Î The ophthalmologist plays a critical role in breaking the chain of transmission of epidemic adenoviral conjunctivitis, primarily by educating the patient and family about proper hygiene. Infected individuals should be counseled to wash hands frequently and use separate towels, and to avoid close contact with others during the period of contagion. Î Wiping with 70% alcohol may not be effective in eliminating adenovirus from tonometer tips. Surfaces should be disinfected with an Environmental Protection Agency (EPA)-registered hospital disinfectant in accordance with the label's use directions and safety precautions. Î Treatment of conjunctivitis is ideally directed at the root cause. Indiscriminate use of topical antibiotics or corticosteroids should be avoided, because antibiotics can induce toxicity and corticosteroids can potentially prolong adenoviral infections and worsen herpes simplex virus infections. Viral conjunctivitis will not respond to anti-bacterial agents, and mild bacterial conjunctivitis is likely to be self-limited. Moreover, the choice of topical antibiotic agent for treatment of bacterial conjunctivitis is empiric since no evidence exists demonstrating the superiority of any particular agent. Î In adults, conjunctivitis caused by ocular mucous membrane pemphigoid (OMMP), graft-versus-host disease (GVHD), gonococcus, and chlamydia is important to detect early because it is necessary to treat the concomitant systemic disorder. Diagnosis of superior limbic keratoconjunctivitis (SLK) may lead to further investigations that reveal a thyroid disorder. Early detection of conjunctivitis associated with neoplasms may be lifesaving.

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