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Conjunctivitis

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15 Seasonal Allergic Conjunctivitis Î Mild allergic conjunctivitis can be treated with an over-the-counter (OTC) antihistamine/vasoconstrictor agent or with the more effective second-generation topical histamine H 1 -receptor antagonists. (I++, G, S) Î If the condition is frequently recurrent or persistent, mast-cell stabilizers can be utilized. (III, I, D) Î Many new medications combine antihistamine activity with mast-cell stabilizing properties and can be utilized for either acute or chronic disease. (I-, M, D) Î If the symptoms are not adequately controlled, a brief course (1–2 weeks) of low-potency topical corticosteroids can be added to the regimen. (III, I, D) Î The lowest potency and frequency of corticosteroid administration that relieves the patient's symptoms should be used. (III, I, D) Î Ketorolac has been FDA-approved for the treatment of allergic conjunctivitis. (I-, M, D) Î Additional measures include using artificial tears, which dilute allergens and treat co-existing tear deficiency, cool compresses, oral antihistamines, and allergen avoidance. (III, I, D) Î Frequent clothes washing and bathing/showering before bedtime may also be helpful. (III, I, D) Î Consultation with an allergist or dermatologist may be helpful for patients who have disease that cannot be adequately controlled with topical medications and oral antihistamines. (III, I, D) Î The use of topical mast cell inhibitors can also be helpful in alleviating the symptoms of allergic rhinitis. (I-, M, D) Î Intranasal corticosteroid therapy, however, is not effective for the treatment of seasonal allergic conjunctivitis. (I-, M, D) Î Frequency of follow-up visits is based on the severity of disease presentation, etiology, and treatment. (III, I, D) Î A follow-up visit should include an interval history, measurement of visual acuity, and slit-lamp biomicroscopy. (III, I, D) Î If corticosteroids are used in chronic or recurrent conjunctivitis, baseline and periodic measurement of IOP and pupillary dilation should be performed to evaluate for cataract and glaucoma. (III, I, D)

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