Comments Pediatric Dose Class (Adult/Child) 15 mg/kg/dose IV q6h B-II
10 mg/kg/dose PO/IV q8h Max: 600 mg/dose
No data B-II C-III/ND
15 mg/kg/dose IV q6h B-II B-II
10 mg/kg/dose PO/IV q8h Max: 600 mg/dose
No data C-III/ND
15 mg/kg/dose IV q6h B-II B-II
10 mg/kg/dose PO/IV q8h Max: 600 mg/dose
No data C-III/ND
Some experts recommend the addition of rifampin 600 mg daily or 300-450 mg bid to vancomycin‡§
for adult patients (B-III). For children ≥ 12 years, linezolid 600 mg bid.
Some experts recommend the addition of rifampin 600 mg daily or 300-450 mg bid to vancomycin‡§
for adult patients (B-III). For children ≥ 12 years, linezolid 600 mg bid.
Some experts recommend the addition of rifampin 600 mg daily or 300-450 mg bid to vancomycin‡§
for adult patients (B-III). For children ≥ 12 years, linezolid 600 mg bid.
15 mg/kg/dose IV q6h B-II/A-II
6-10 mg/kg/day IV daily
10 mg/kg/dose PO/IV q8h Max: 600 mg/dose
If stable: 10-13 mg/kg/dose
PO/IV q6-8h Max: 40 mg/kg/day
No data B-II/ND B-II/C-III B-II/C-III B-III/A-II
Some experts recommend the addition of rifampin 600 mg daily or 300-450 mg bid to the chosen antibiotic (B-III). For patients with concurrent bacteremia, rifampin should be added aſter clearance of bacteremia.
For children ≥ 12 years, linezolid 600 mg PO/IV bid should be used. A single-strength and double-strength tablet of TMP-SMX‡
TMP, respectively. For an 80 kg adult, 2 DS tablets achieves a dose of 4 mg/kg.
Magnetic resonance imaging (MRI) with gadolinium is the imaging modality of choice, particularly for detection of early osteomyelitis and associated soſt tissue disease (A-II).
Erythrocyte sedimentation rate (ESR) and/or C-reactive protein (CRP) may be helpful to guide response to therapy (B-III).
§ Max: 2 gm/dose. In seriously ill patients consider a loading dose of 25-30 mg/kg (C-III). 9 contains 80 mg and 160 mg of
