IDSA GUIDELINES Bundle (free trial)

Complicated Intra-Abdominal Infection

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Table 4. Strength of Recommendation and Quality of Evidence Category/Grade Definition Strength of Recommendation A B C Quality of Evidence I II III Good evidence to support a recommendation for or against use. Moderate evidence to support a recommendation for or against use. Poor evidence to support a recommendation. Evidence from ≥ 1 properly randomized, controlled trial. Evidence from ≥ 1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from > 1 center); from multiple time- series; or from dramatic results of uncontrolled experiments. Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees. Source: The periodic health examination. Canadian Task Force on the Periodic Health Examination. Health Canada, 1979. Adapted and Reproduced with the permission of the Minister of Public Works and Government Services Canada, 2009. Abbreviations g, gram; GNR, gram-negative rod; h, hour(s); IDSA, Infectious Diseases Society of America; kg, kilogram; MDR, multi-drug resistant; mg, milligram; MRI, magnetic resonance imaging; q, every; US, ultrasonography; yr, year(s) Source Solomkin JS, Mazuski JE, Bradley JS, et al. Diagnosis and Management of Complicated Intra- abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Clin Infect Dis. 2010;50(2):133-64. Erratum in: Clin Infect Dis. 2010;50(12):1695. [PMID: 20034345] Disclaimer This Guideline attempts to define principles of practice that should produce high-quality patient care. It focuses on the needs of primary care practice, but also is applicable to providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aſter consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. 5740 Executive Drive Suite 220 Baltimore, MD 21228 TEL: 410-869-3332 • FAX: 410-744-2150 For additional copies: Copyright © 2010 All rights reserved 9

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