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Primary Stroke Prevention

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7 Table 14. Migraine Recommendations COR LOE Smoking cessation should be strongly recommended in women with migraine headaches with aura. I B Alternatives to OCs, especially those containing estrogen, might be considered in women with active migraine headaches with aura. IIb C Treatments to reduce migraine frequency might be reasonable to reduce the risk of stroke. IIb C Closure of PFO is NOT indicated for preventing stroke in patients with migraine. III B Table 15. Metabolic Syndrome Recommendation Management of individual components of the metabolic syndrome is recommended, including lifestyle measures (ie, exercise, appropriate weight loss, proper diet) and pharmacotherapy (ie, medications for BP lowering, lipid lowering, glycemic control, and antiplatelet therapy), as endorsed in other sections of this guideline. (Refer to relevant sections for Class and Levels of Evidence for each recommendation.) Table 16. Alcohol Consumption Recommendations COR LOE Reduction or elimination of alcohol consumption in heavy drinkers through established screening and counseling strategies as described in the 2004 US Preventive Services Task Force update is recommended. I A For individuals who choose to drink alcohol, consumption of ≤2 drinks per day for men and ≤1 drink per day for nonpregnant women might be reasonable. IIb B Table 17. Drug Abuse Recommendation COR LOE Referral to an appropriate therapeutic program is reasonable for patients who abuse drugs that have been associated with stroke, including cocaine, khat, and amphetamines. IIa C Table 18. Sleep-Disordered Breathing Recommendations COR LOE Because of its association with stroke risk, screening for sleep apnea through a detailed history, including structured questionnaires such as the Epworth Sleepiness Scale and Berlin Questionnaire, physical examination, and, if indicated, polysomnography may be considered. IIb C Treatment of sleep apnea to reduce the risk of stroke may be reasonable, although its effectiveness for primary prevention of stroke is unknown. IIb C

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