8
Treatment
Table 7. Oral Antihistamines
Medication
FDA Indications
(seasonal,
perennial) Contraindications Approved Ages
Cetirizine (Zyrtec) Seasonal AR
Perennial AR
Hypersensitivity to
cetirizine, levocetirizine
or hydroxyzine
≥6 mo
Levocetirizine
(Xyzal)
Seasonal AR
Perennial AR
Hypersensitivity to
levocetirizine, cetirizine
or hydroxyzine
≥6 mo
Fexofenadine
(Allegra)
Seasonal AR Hypersensitivity to
fexofenadine
≥2 yrs
Loratadine
(Claritin, Alavert)
Seasonal AR
Perennial AR
Hypersensitivity
to loratadine or
desloratadine
≥2 yrs
Desloratadine
(Clarinex)
Seasonal AR
Perennial AR
Hypersensitivity
to desloratadine or
loratadine
≥6 mo
Table 8. Intranasal Antihistamines
Medication
FDA Indications
(seasonal,
perennial) Contraindications
Approved
Ages
Olopatadine (Patanase)
(as HCl) 0.6%
(665 mcg/spray)
Seasonal AR None ≥6 yrs
Azelastine (Astelin)
0.1% solution (137mcg/spray)
Seasonal AR
Vasomotor rhinitis
None ≥6 yrs
Azelastine (Astepro)
0.15% solution
(205.5 mcg/spray)
Seasonal AR
Perennial AR
None ≥6 yrs
Azelastine plus fluticasone
(Dymista)
(137 mcg azelastine, 50 mcg
fluticasone per spray)
Seasonal AR None ≥12 yrs
