17
Figure 4. Strategies for Rhythm Control in Patients With
Paroxysmal
a
and Persistent AF
b
No Structural
Heart Disease
CAD HF
Dofetilide
d,e
Dronedarone
Flecainide
d,f
Propafenone
d,f
Sotalol
d,e
Catheter
ablation
Dofetilide
d,e
Dronedarone
Sotalol
d,e
Catheter
ablation
Structural
Heart Disease
Amiodarone
Dofetilide
d,e
Amiodarone Amiodarone
a
Catheter ablation is only recommended as first-line therapy for patients with paroxysmal AF
(Class IIa recommendation).
b
Drugs are listed alphabetically.
c
Depending on patient preference when performed in experienced centers.
d
Not recommended with severe LVH (wall thickness >1.5 cm).
e
Should be used with caution in patients at risk for torsades de pointes ventricular tachycardia.
f
Should be combined with AV nodal blocking agents.
c
c