ACC GUIDELINES Bundle (free trial)

Atrial Fibrillation

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49 Factor Xa Inhibitor Rivaroxaban Apixaban Edoxaban Avoid use Avoid use Avoid use with rifampin. No study evaluated the effect of other p-glycoprotein/ CYP 3A4 inducers on edoxaban drug levels No dose adjustment needed No dose adjustment needed No dose adjustment needed Avoid use Use with caution Use with caution Avoid use Avoid use Avoid use

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