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Atrial Fibrillation

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45 Anticoagulation choice Anticoagulation reasonable if 1%–2%/y (2a) Anticoagulation recommended if ≥2%/y (1) DOACs preferred over warfarin (except for mitral stenosis or mechanical heart valve) (1) Aspirin either alone or with clopidogrel not recommended to reduce stroke risk (3: Harm) Stroke and systemic embolism event risk threshold for anticoagulation If no risk factors for stroke, aspirin to prevent thromboembolic events not recommended (3: No benefit) Figure 10. Antithrombotic Options in Patients with AF

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