45
Anticoagulation
choice
Anticoagulation
reasonable if
1%–2%/y
(2a)
Anticoagulation
recommended if
≥2%/y
(1)
DOACs preferred
over warfarin (except
for mitral stenosis
or mechanical heart
valve)
(1)
Aspirin either alone
or with clopidogrel
not recommended
to reduce stroke risk
(3: Harm)
Stroke and
systemic
embolism event
risk threshold for
anticoagulation
If no risk factors
for stroke, aspirin
to prevent
thromboembolic
events not
recommended
(3: No benefit)
Figure 10. Antithrombotic Options in Patients with AF
