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Atrial Fibrillation 2023 Update

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124 Management 10.11. Hyperthyroidism COR LOE Recommendation 1 B-NR 1. In patients with hyperthyroidism and AF who have an elevated risk of stroke based on a standard clinical risk score, anticoagulation is recommended until thyroid function has returned to normal and sinus rhythm can be maintained. 10.12. Pulmonary Disease COR LOE Recommendations 2a B-R 1. In patients with AF and COPD, it is reasonable to use cardioselective beta blockers for rate control of AF, especially where other indications exist, such as MI and HF. 2a B-NR 2. In patients with pulmonary hypertension with pulmonary vascular disease (PH PVD ) and AF or AFL, a rhythm-control strateg y is reasonable to improve functional status and potentially prolong survival. 10.13. Pregnancy COR LOE Recommendations 1 B-NR 1. In pregnant patients with AF, DCCV is safe to the patient and fetus and should be performed in the same manner as in patients who are not pregnant. 2b C-LD 2. In pregnant individuals with structurally normal hearts and hemodynamically stable AF, pharmacological cardioversion with agents with history of safe use in pregnancy, such as intravenous procainamide, may be considered. 2a C-LD 3. In pregnant individuals with AF and without structural heart disease, antiarrhythmic agents with history of safe use in pregnancy, such as flecainide and sotalol, are reasonable for maintenance of sinus rhythm. 2a B-NR 4. In pregnant individuals with persistent AF, rate-control agents with a record of safety in pregnancy, such as beta blockers (eg, propranolol or metoprolol) and digoxin, either alone or in combination with beta blockers, are reasonable as first-line agents. 2b C-LD 5. Pregnant individuals with AF and elevated risk of stroke may be considered for anticoagulation with the recognition that no anticoagulation strateg y is completely safe for both the mother and fetus, and an SDM discussion should take place regarding risks to both mother and fetus (see Table 28).

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