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Atrial Fibrillation 2023 Update

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113 Uncontrolled rate with biventricular pacemaker in place without effective pacing %: AV Nodal ablation (2a) HFrEF (LVEF ≤50%) Uncontrolled rate + rhythm control failed or not appropriate: AV nodal ablation + pacing (2a) Left bundle or His bundle pacing (HBP) as alternative to biventricular pacing (2b) Repeat ablation Decision for pharmacological rhythm- vs. rate-control strategy Pharmacological cardioversion and maintenance of sinus rhythm after cardioversion (See sections 8.2.3 and 8.3.1) Less likely to benefit from catheter ablation • Advanced HF • Significant ventricular scar on CMR • Severe atrial myopathy (dilation/fibrosis) • Long-standing persistent AF • Prior failed ablations • Advanced age or multiple comorbidities Dronaderone NYHA Class III/IV HF or decompensated HF in past 4 wk (3: Harm)

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