Diagnosis
10
Table 3. Definitions of Prediabetes (Intermediate Glycemia)
Prediabetes Category
IFG IGT
High Risk
for DM by
A1c
Organization
Fasting
Glucose 2-hour OGTT
Hemoglobin
A1c Comments
ADA
a
100–125 mg/dL
(5.6–6.9
mmol/L)
140–199 mg/dL
(7.8–11.0
mmol/L)
5.7–6.4%
(39–46
mmol/mol)
Any one of
the three is
sufficient.
WHO 2011
b
110–125 mg/dL
(6.1–6.9
mmol/L)
140–199 mg/dL
(7.8–11.0
mmol/L)
A1c is not
recommended
for diagnosis
of intermediate
glycemia.
IEC 2003
c
100-125 mg/dL
(6.1–6.9
mmol/L)
FPG lower
threshold
was revised
downward
from previous
1997 report to
include more
individuals.
IEC 2009
d
6.0–6.4%
(42–46
mmol/mol)
Restricted
to higher
risk group
than ADA
definition
for T2DM
prevention.
a
Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes. Diabetes Care
2019; 42 Suppl 1: S13-S28.
b
World Health Organization. Use of glycated haemoglobin (HbA1c) in the diagnosis of diabetes
mellitus: abbreviated report of a WHO consultation. 2011 www.who.int/diabetes/publications/
diagnosis_diabetes2011/en/index.html.
c
e Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Follow-up Report
on the Diagnosis of Diabetes Mellitus. Diabetes Care 2003 Nov; 26(11): 3160-3167. https://doi.
org/10.2337/diacare.26.11.3160.
d
e International Expert Committee. International Expert Committee report on the role of the
A1C assay in the diagnosis of diabetes. Diabetes Care. 2009; 32(7):1327-34.
