Diagnosis
4
Figure 1. Fetal Adrenal Steroidogenesis
Cholesterol
Pregnenolone
P450scc
+ StAR
17OH-Preg
P450c17
DHEA
P450c17+b
5
3βHSD2
Progesterone
P450c21
3βHSD2
17OH-Progesterone
(17OHP)
P450c21
3βHSD2
Androstenedione
P450c11β
Androstenediol
17βHSD5
3βHSD2
Testosterone
5αR2
DHT
Cholesterol
Pregnenolone
17OH-Preg
DHEA
Androstenediol
P450scc
+ StAR
P450c17
P450c17+b
5
17βHSD5
170HP
3βHSD2 5αR1
5α-Pregnan-
17α-ol-3,
20-dione
Reductive
3αHSD
P450c17
17βHSD5
Androstenedione
3βHSD2
P450c17+b
5
Testosterone
5αR2
DHT
17βHSD5
3βHSD2
Oxidative
3αHSD
(a)
(b)
