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Testosterone Therapy in Men with Hypogonadism

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106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at GuidelineCentral.com Copyright © 2018 All rights reserved ESTES1863 Disclaimer is pocket guide attempts to define principles of practice that should produce high-quality patient care. It focuses on the needs of primary care practice, but also is applicable to providers at all levels. is pocket guide should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. e ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aer consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. Source Bhasin S et al. Testosterone erapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab., May 2018, 103(5):1–30. Abbreviations AAS, androgenic-anabolic steroid; ACTH, adrenocorticotropic hormone; AUA, America Urological Association; BMD, bone mineral density; CDC, Centers for Disease Control and Prevention; CT, computed tomography; DHT, dihydrotestosterone; DRE, digital rectal examination; E2, estradiol; ES, Endocrine Society; FDA, US Food and Drug Administration; FSH, follicle stimulating hormone; FT, free testosterone; IM, intramuscular; IPSS, International Prostate Symptom Score; KS, Klinefelter syndrome; LH, luteinizing hormone; LUTS, lower urinary tract symptoms; PSA, prostate-specific antigen; SC, subcutaneous; SHBG, sex hormone-binding globulin; SMD, standardized mean difference; T, testosterone; TT, total testosterone Grading System Strength of Recommendation 1 = strong 2 = conditional UGPS = ungraded good practice statement Quality of Evidence ⊕⊕⊕⊕ = high ⊕⊕⊕ = moderate ⊕⊕ = low ⊕ = very low

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