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HIV Primary Care

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9 Screening for Syphilis Î All patients should be screened for syphilis upon initiation of care and periodically thereafter, depending on risk (SR-H). Î A lumbar puncture should always be performed for patients with a reactive syphilis serology who have neurologic or ocular symptoms or signs, irrespective of past syphilis treatment history (SR-H). Î A lumbar puncture should be performed in patients who experience serologic treatment failure (ie, whose nontreponemal titers fail to decline 4-fold after stage-appropriate therapy, or whose titers increase 4-fold if reinfection is ruled out) (WR-L). Screening for Other Sexually Transmitted Diseases Î All women should be screened for trichomoniasis, and all women ≤25 years of age should be screened for Chlamydia trachomatis infection (SR-H). Î Men and women should be screened for gonorrhea and chlamydia infection at initial presentation and then annually if at risk for infection (SR-H). Î Retesting in 3 months is indicated in men and women found to be positive for gonorrheal and chlamydial infections and women found to be positive for trichomoniasis on initial screening, because of high reinfection rates (SR-M). Î Patients should be screened for all of these conditions periodically thereafter, depending on the population, reported behaviors, the presence of other sexually transmitted diseases (STDs) in the patient or his/her partner(s), and the prevalence of STDs in the community (SR-L). Cervical Cancer Screening and Prevention Î HIV-infected women should have a cervical Pap smear performed upon initiation of care, and this test should be repeated at 6 months and annually thereafter if results are normal (SR-M). Î Women with atypical squamous cells (both ASC-US [atypical squamous cells of unknown significance] and ASCH [ASC, cannot rule out high-grade squamous intraepithelial lesion]), atypical glandular cells, low-grade or high-grade squamous intraepithelial lesion, or squamous carcinoma noted by Pap testing should undergo colposcopy and directed biopsy, with further treatment as indicated by results of the evaluation (SR-H).

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