18
Selecting a Treatment Regimen
Table 7b. HIV Drugs (continued)
Drug Name Formulations Dosing Recommendations
a
Characteristics of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
Efavirenz
(EFV)
Sustiva
®
Also available as a
component of fixed-dose
combination.
• 50 and 200 mg
capsules
• 600 mg tablet
• 600 mg once daily, at or before bedtime
• Take on an empty stomach to reduce
side effects.
Rilpivirine
(RPV)
Edurant
®
Also available as a
component of fixed-dose
combination.
25 mg tablet • 25 mg once daily
• Take with a meal.
Drug Name Formulations Dosing Recommendations
a
Characteristics of Protease Inhibitors (PIs)
Atazanavir
(ATV)
Reyataz
®
100, 150, 200, and
300 mg capsules
ARV-Naive Patients:
• ATV 300 mg + RTV 100 mg once
daily; or
• ATV 400 mg once daily
With TDF or in ARV- Experienced
Patients:
• ATV 300 mg + RTV 100 mg once daily
With EFV in ARV-naive patients:
• ATV 400 mg + RTV 100 mg once daily
• Take with food.
Darunavir
(DRV)
Prezista
®
• 75, 150, 600,
and 800 mg
tablets
• 100 mg/mL
oral suspension
ARV-Naive Patients or ARV-
Experienced Patients with no DRV
Mutations:
• DRV 800 mg + RTV 100 mg once daily
ARV-Experienced Patients with at Least
1 DRV Mutation:
• DRV 600 mg + RTV 100 mg bid
• DRV inactive without boosting
• Take with food.
