Antiretroviral Agents in HIV-1 (2014)

DHHS Adult HIV 2014

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16 Selecting a Treatment Regimen Table 7b. Commonly used Antiretroviral Agents Generic Name (Abbreviation) Trade Name Formulations Dosing Recommendations a Characteristics of Nucleoside Reverse Transcriptase Inhibitors (NRTIS) Abacavir (ABC) Ziagen ® Note: Generic available in tablet formulation Also available as a component of fixed- dose combinations. Ziagen ® : • 300 mg tablet • 20 mg/mL oral solution Ziagen ® : • 300 mg bid, or • 600 mg once daily • Take without regard to meals. Emtricitabine (FTC) Emtriva ® Also available as a component of fixed- dose combinations. Emtriva ® : • 200 mg hard gelatin capsule oral Emtriva ® Capsule: • 200 mg once daily Oral Solution: • 240 mg (24 mL) once daily • Take without regard to meals. Lamivudine (3TC) Epivir ® Note: Generic available in tablet formulation Also available as a component of fixed- dose combinations. Epivir ® : • 150 and 300 mg tablets • 10 mg/mL oral solution Epivir ® : • 150 mg bid, or • 300 mg once daily • Take without regard to meals. Tenofovir Disoproxil Fumarate (TDF) Viread ® Also available as a component of fixed- dose combinations. Viread ® : • 150, 200, 250, 300 mg tablets • 40 mg/g oral powder Viread ® : • 300 mg once daily or • 7.5 level scoops once daily (dosing scoop dispensed with each prescription; one level scoop contains 1 g of oral powder). • Take without regard to meals. • Mix oral powder with 2-4 ounces of a soft food that does not require chewing (eg, applesauce, yogurt). Do not mix oral powder with liquid.

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