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Vaccination of the Immunocompromised Host

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International Travel 12. Clinicians may administer inactivated vaccines indicated for travel based on the CDC annual schedule for immunocompetent adults and children (SR-L). 13. Yellow fever vaccine generally should NOT be administered to immunocompromised persons (SR-M). If travel to an endemic area cannot be avoided, vaccination can be considered in certain adults with human immunodeficiency virus (HIV) infection who are minimally immunocompromised: a. Asymptomatic HIV-infected adults with CD4 T-cell lymphocyte counts of ≥200 cells/mm 3 (WR-L) b. Asymptomatic HIV-infected children age 9 months through 5 years with CD4 T-cell lymphocyte percentages of ≥15% (WR-VL) 14. With certain exceptions (eg, yellow fever vaccine and MMR in certain HIV-infected patients [see recommendation 13 and HIV section] and MMR in certain HSCT patients [see HSCT section]), live vaccines should NOT be given to immunocompromised persons (SR-L). Key Points 4

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