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Vaccination of the Immunocompromised Host

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18 Special Populations 82. Administer 3 doses of HepB starting at 6-12 months after HSCT (SR-M). If a postvaccination anti-HBs concentration of ≥10 mIU/mL is not attained, a second 3-dose series of HepB (SR-L) (Alternative: 1 dose of HepB after which anti-HBs is tested*) using standard dose (SR-M) or high dose (40 μg)* (WR-L) for children and high dose for adolescents* and adults (SR-L) should be administered. 83. Administer 3 doses of IPV starting 6-12 months after HSCT (SR-M). 84. Consider administration of 3 doses of HPV starting at 6-12 months after HSCT for female patients ages 11-26 years and HPV4 in males ages 11-26 years (WR-VL). 85. Do not administer live vaccines to HSCT patients with active GVHD or ongoing immunosuppression (SR-L). 86. Administer a 2-dose series of MMR to measles-seronegative adolescents and adults (SR-L) and to measles-seronegative children (SR-M) starting 24 months after HSCT in patients with neither chronic GVHD nor ongoing immunosuppression and 8-11 months (or earlier if in a measles outbreak situation) after the last dose of immune globulin intravenous (IGIV). 87. Administer a 2-dose series of VAR starting 24 months after HSCT to varicella-seronegative patients with neither GVHD nor ongoing immunosuppression and 8-11 months after the last dose of IGIV (SR-L).

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