Table 2. Vaccination of Persons With HIV Infection Footnotes
R, recommended—administer if not previously administered or not current; such patients may be at
increased risk for this vaccine-preventable infection
U, usual—administer if patient not current with recommendations for dose(s) of vaccine for
immunocompetent persons in risk and age categories
X, contraindicated.
a
Asymptomatic HIV infection with CD4 T-lymphocyte counts of 200–499 cells/mm
3
for adults and
adolescents and percentage of 15%-24% for infants and children.
b
CD4 T-lymphocyte count of <200 cells/mm
3
for adults and adolescents and percentage of <15%
for infants and children.
c
1 dose.
d
High-dose HepB (40 µg ) should be considered for adults (WR-M) and adolescents (WR-L) with
HIV infection. e latter recommendation deviates from CDC ACIP recommendations.
e
HPV4 is preferred over HPV2 because of its activity against genital warts, a recommendation for
administration of a vaccine that deviates from CDC ACIP recommendations.
f
LAIV may be considered in otherwise healthy HIV-infected patients age 5-17 years on a highly
active antiretroviral therapy (HAART) regimen for ≥16 weeks with CD4 T-lymphocyte percentage
of ≥15% and HIV plasma RNA of <60,000 copies.
g
For HIV-infected patients, MCV4 is administered as a 2-dose primary series separated by
≥2 months. A booster dose (third dose) should be administered at age 16 years if the initial series
was given at age 11-12 years and at age 16-18 years if the initial series was given at age 13-15 years.
h
For patients not fully vaccinated with PCV13 by previous administration.
i
For patients ≥19 years of age with HIV who have previously received PPSV23, PCV13 should be
administered aer an interval of ≥1 year aer the last PPSV23 dose (WR-L).
j
PPSV23 should be administered 8 weeks or longer aer indicated dose(s) of PCV13. A second dose
of PPSV23 should be administered 5 years aer the initial dose.
k
Vaccination can be considered for patients 50 through 59 years of age not previously vaccinated
with varicella vaccine (weak, low), a recommendation for administration of a vaccine that deviates
from recommendations of the Advisory Committee on Immunization Practices, Centers for Disease
Control and Prevention.
l
For patients not vaccinated with varicella vaccine.
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