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Vaccination of the Immunocompromised Host

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60. HepB containing 20 μg of HBsAg (hepatitis B surface antigen) combined with HepA (HepA-HepB; Twinrix ® ) 3-dose series can be used for primary vaccination of HIV-infected patients ≥12 years of age (SR-M).* 61. Internationally adopted HIV-infected children who had prior doses of OPV should receive a total of 4 doses of a combination of OPV and IPV vaccines (SR-L). 62. HPV4 is recommended over bivalent human papillomavirus vaccine (HPV2) because HPV4 prevents genital warts (SR-L),* although there are no data on differences between the vaccines for preventing cervical dysplasia in HIV-infected women. Live Vaccines 63. HIV-exposed or -infected infants should receive rotavirus vaccine according to the schedule for uninfected infants (SR-L). 64. HIV-infected patients should NOT receive LAIV (WR-VL). 65. MMR should be administered to clinically stable HIV-infected children 1-13 years old without severe immunosuppression (SR-M) and HIV-infected patients ≥14 years without measles immunity and with a CD4 T-cell lymphocyte count of ≥200/mm 3 (WR-VL). 66. HIV-infected children with a CD4 T-cell percentage of <15% (SR-M) or patients ≥14 years with a CD4 T-cell lymphocyte count of <200 cells/mm 3 should not receive MMR (SR-M). 67. HIV-infected patients should NOT receive quadrivalent MMR- varicella vaccine (MMRV) (SR-VL). 68. Varicella-nonimmune, clinically stable HIV-infected patients age 1-8 years with ≥15% CD4 T-lymphocyte percentage (SR-H), age 9-13 years with ≥15% CD4 T-lymphocyte percentage (SR-VL), and age ≥14 years with CD4 T-lymphocyte counts of ≥200 cells/mm 3 should receive VAR (SR-VL). The 2 doses should be separated by ≥3 months (SR-M). 11

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