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Vaccination of the Immunocompromised Host

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Special Populations 24 Table 5. Vaccinations Prior to or After Solid Organ Transplant Footnotes R, recommended—administer if not previously administered or not current; such patients may be at increased risk for this vaccine-preventable infection U, usual—administer if patient not current with recommendations for dose(s) of vaccine for immunocompetent persons in risk and age categories X, contraindicated. a Consider hepatitis B vaccine for hepatitis B-infected liver transplant patients (WR-L). b IIV may be administered to SOT recipients despite intensive immunosuppression (eg, during the immediate posttransplant period), particularly in an outbreak situation (WR-L). c Administer only if patient is not immunosuppressed and the timing is ≥4 weeks prior to transplant. d Administer only if patient is nonimmune, not severely immunosuppressed, and the timing is ≥4 weeks prior to transplant. e For patients ≥19 years who have previously received PPSV23, PCV13 should be administered aer an interval of ≥1 year aer the last PPSV23 dose (WR-L). f Administer only if patient is not immunosuppressed and the timing is ≥4 weeks prior to transplant.* g Selected seronegative patients with a renal or liver transplant have been safely vaccinated.* h Administer only if patient is not severely immunosuppressed, the timing is ≥4 weeks prior to transplant, and the patient is varicella-immune as defined by documentation of age-appropriate varicella vaccination, serologic evidence of immunity, documentation of varicella or zoster infection, or birth in the United States before 1980. * i Administer only if patient is not severely immunosuppressed and the timing is ≥4 weeks prior to transplant. * is recommendation deviates from CDC ACIP recommendations.

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