Diagnosis
Diagnosis
Table 1. Recommendations for Risk Assessment
Recommendations
ACC/AHA
COR
ACC/AHA
LOE
e race- and sex-specific Pooled Cohort Equations
a
to predict
10-year risk for a first hard ASCVD event should be used in non-
Hispanic African Americans and non-Hispanic Whites, 40-79
years of age.
I B
Use of the sex-specific Pooled Cohort Equations for non-
Hispanic Whites may be considered when estimating risk in
patients from populations other than African Americans and
non-Hispanic Whites.
IIb C
If, aer quantitative risk assessment, a risk-based treatment
decision is uncertain, assessment of 1 or more of the following—
family history, hs-CRP, CAC score, or ABI—may be considered
to inform treatment decision making. (See Table 2)
IIb
b
B
e contribution of ApoB, CKD, albuminuria, and
cardiorespiratory fitness to risk assessment for a first ASCVD
event is uncertain at present.
N/A N/A
Routine measurement of CIMT is not recommended in clinical
practice for risk assessment for a first ASCVD event.
III: No
Benefit
b
B
It is reasonable to assess traditional ASCVD risk factors
c
every
4-6 years in adults 20-79 years of age who are free from ASCVD
and to estimate 10-year ASCVD risk every 4-6 years in adults
40-79 years of age who are free from ASCVD.
IIa B
Assessing 30-year or lifetime ASCVD risk based on traditional
risk factors
c
may be considered in adults 20-59 years of age
who are free from ASCVD and are not at high short-term risk.
IIb C
a
Derived from the Atherosclerosis Risk in Communities (ARIC) study, Cardiovascular Health Study
(CHS), Coronary Artery Risk Development in Young Adults (CARDIA) study, Framingham original and
offspring cohorts.
b
Based on new evidence reviewed during ACC/AHA update of evidence.
c
Age, sex, total cholesterol, high-density lipoprotein cholesterol, systolic BP, use of antihypertensive therapy,
diabetes, and current smoking.
