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Abbreviations bid, twice a day; h, hour(s); IBS, irritable bowel syndrome; OBD, opioid bowel dysfunction; g, gram; OIC, opioid-induced constipation; PO, by mouth; subcut, subcutaneous Source Fakata KL, Cole BE. Peripheral opioid antagonists: a therapeutic advance for optimizing opioid gastrointestinal tolerability. J Fam Pract. 2007 Jun;56(6 Suppl Peripheral):S3-12. Disclaimer This Guideline attempts to define principles of practice that should produce high-quality patient care. It focuses on the needs of primary care practice, but also is applicable to providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician after consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. OIC061111 106 Commerce Street, Suite 105 Lake Mary, FL 32746  TEL: 407.878.7606 • FAX: 407.878.7611   For additional copies: info@GuidelineCentral.com Copyright © 2011 All rights reserved

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