Abbreviations
ABI, ankle-brachial index; C&S, culture and sensitivity; CPK, creatine phosphokinase;
DFI, diabetic foot infection; DFO, diabetic foot osteomyelitis; ESBL, extended-spectrum
β-lactamase; FDA, US Food and Drug Administration; GPC, Gram-positive cocci;
GRADE, Grading of Recommendations Assessment, Development and Evaluation;
IDSA, Infectious Diseases Society of America; IV, intravenous; IWGDF, International
Working Group on the Diabetic Foot; MIC, minimum inhibitory concentration; MRI,
magnetic resonance imaging; MRSA, methicillin-resistant Staphylococcus aureus; MSSA,
methicillin-sensitive S. aureus; PEDIS, perfusion, extent, depth, infection, sensation
(IWGDF research scoring); PO, oral; prn, as needed; PTB, probe to bone; qid, four
times a day; RCT, randomized controlled trial; SIRS, systemic inflammatory response
syndrome; tid, three times a day
Source
Lipsky BA, Berendt AR, Cornia PB, Pile JC, Peters EJG, Armstrong DG, Deery HG,
Embil JM, Joseph WS, Karchmer AW, Pinzur MS, Senneville E. 2012 Infectious Diseases
Society of America Clinical Practice Guideline for the Diagnosis and Treatment of Diabetic Foot Infections. Clinical Infectious Diseases 2012;54(12):132–173.
Disclaimer
This Guideline attempts to define principles of practice that should produce high-quality patient
care. It is applicable to specialists, primary care, and providers at all levels. This Guideline
should not be considered exclusive of other methods of care reasonably directed at obtaining the
same results. The ultimate judgment concerning the propriety of any course of conduct must be
made by the clinician after consideration of each individual patient situation.
Neither IGC, the medical associations, nor the authors endorse any product or service associated
with the distributor of this clinical reference tool.
Tables in this guideline provide a concise summary; they should be used in the context of all of
the evidence and recommendations made in the full guideline.
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