Primary Care Management of HIV-Infected Patients

Primary Care Management of HIV-Infected Patients

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Screening for Syphilis ÎÎAll patients should be screened for syphilis upon initiation of care and periodically thereafter depending on risk (A-II). ÎÎA lumbar puncture should always be performed in patients with reactive syphilis serology and neurologic or ocular symptoms or signs and in patients with late latent syphilis (> 1 year's duration) (A-II). ÎÎPatients who experience serologic treatment failure should also undergo lumbar puncture (B-III). Screening for Ano-Genital Human Papillomavirus (HPV) ÎÎHIV-infected men and women with HPV infection are at increased risk for anal dysplasia and cancer. Men who have sex with men, women with a history of abnormal cervical Pap test, and all HIV infected persons with genital warts should be considered for ano-genital HPV screening and anal Pap tests (C-III). Serum Testosterone Level ÎÎProviders should consider obtaining a morning serum total testosterone level in male patients who complain of fatigue, weight loss, loss of libido or erectile dysfunction, or depressive symptoms or who have evidence of reduced bone mineral density (C-III). Other Laboratory Tests ÎÎRoutine testing for cryptococcal infection by determination of serum cryptococcal antigen or for disseminated Mycobacterium avium complex infection by culture of blood for acid-fast bacilli is not recommended (B-II). Chest Radiography ÎÎA baseline chest radiograph should be obtained in all HIV-infected patients with a positive TB screening test to rule out active tuberculosis and may also be useful in other patients who are likely to have pre-existing lung abnormalities (B-III). Staging ÎÎPatients may be staged according to the CDC AIDS Surveillance Definition for epidemiologic and reporting purposes (C-III). (Table 1) Table 1. Centers for Disease Control and Prevention (CDC) Staging System for Classification of HIV-Infected Adults CDC Classification CD4 cell count, cells/mm3 (CD4 cell percentage) B C ≥ 500 (≥ 29%) 200-500 (14%-28%) < 200 (< 14%) 6 A A1 A2 A3 B1 B2 B3 C1 C2 C3

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