51
Adverse events Monitoring Duration
Viral infections CBC with diff, liver panel, chem
10, viral PCR
Lifelong or until
transplant
Cytopenias
Liver enzyme elevations,
elevated triglycerides
Medication interactions Whole blood ADA level, CBC,
lymphocyte subsets
Until transplant
Injection site reactions,
infection
CRP, ESR, SAA Lifelong
Injection site reactions,
infection
CRP, ESR, SAA Lifelong
Injection site reactions,
infection
CRP, ESR, SAA Lifelong
Live vaccines should not be
given concurrently or within
3 mo of discontinuation
None Lifelong
Do not give with TNF
inhibitors
Teratogenic CBC Lifelong
CBC Lifelong
None CBC, vitamin B12 Lifelong
Folate
None CBC, vitamin B12 Lifelong
Folate
Liver enzyme elevations Liver enzymes Lifelong or until
transplant
Renal toxicity, fever Chem 10
CBC with diff
Possible fetal harm CBC Lifelong
Medication interactions Immunoglobulin
