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Section 9. Infection Prevention in Inborn Errors of Immunity
Recommendation 9.1
➤ We recommend targeted antimicrobial prophylaxis for patients with
IEI and increased susceptibility to infections. (S-H)
Recommendation 9.2
➤ We recommend using only irradiated, CMV-negative, lymphocyte-
depleted blood products for administration to patients with combined
immunodeficiencies or athymia. (S-M)
Recommendation 9.3
➤ We recommend educating patients regarding environmental exposures
that may increase the risk of infections for patients with IEI. (S-M)
Recommendation 9.4
➤ We suggest prompt diagnostic testing in patients with IEI with acute
infection symptoms and the use of antimicrobial regimens with duration
longer than recommended for immunocompetent patients. (C-L)