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Inborn Errors of Immunity

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27 Section 9. Infection Prevention in Inborn Errors of Immunity Recommendation 9.1 ➤ We recommend targeted antimicrobial prophylaxis for patients with IEI and increased susceptibility to infections. (S-H) Recommendation 9.2 ➤ We recommend using only irradiated, CMV-negative, lymphocyte- depleted blood products for administration to patients with combined immunodeficiencies or athymia. (S-M) Recommendation 9.3 ➤ We recommend educating patients regarding environmental exposures that may increase the risk of infections for patients with IEI. (S-M) Recommendation 9.4 ➤ We suggest prompt diagnostic testing in patients with IEI with acute infection symptoms and the use of antimicrobial regimens with duration longer than recommended for immunocompetent patients. (C-L)

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