Hyperthyroidism
36
Figure
5.
Strategy
for
ATD
Discontinuation
Upon
Pregnancy
Confirmation
a
For
MMI/CMZ,
the
teratogenic
period
ends
at
approximately
16
weeks
for
skin
defects,
while
the
risks
for
other
congenital
anomalies
remain
elevated
generally
throughout
the
first
trimester.
b
e
1
year
risk
of
Graves'
disease
relapse
typically
ranges
between
30–70%
following
ATD
discontinuation
based
on
risk
factors
in
the
text.
Conception
Week
5
Week
10
Week
20
Birth
TSH
Receptor
Abs
and/or
TSI
Graves'
hyperthyroidism
relapse
risk
b
STOP
PTU/MMI
