Hyperthyroidism
32
Recommendations Table 15. Subclinical and Overt
Hyperthyroidism in Pregnancy
Strength
*
Level
#
Subclinical hyperthyroidism or GTT should not be
treated with ATD therapy, but propranolol may be used to
ameliorate hyperthyroidism-related palpitations.
Strong Moderate
In pregnant women with subclinical hyperthyroidism whose
TSH concentration is <0.1 mU/L, serum thyroid function
should be monitored without treatment every 2–4 weeks.
Good Practice Statement
Overt hyperthyroidism that is not due to GTT (i.e., Graves'
disease, autonomous thyroid nodule) should be treated, to
minimize the duration of uncontrolled thyrotoxicosis in
pregnancy.
Good Practice Statement
Overt hyperthyroidism not due to GTT (i.e., Graves' disease,
autonomous thyroid nodule) may be treated with ATD
therapy, targeting a FT4 concentration at or slightly above
the upper third of the reference interval.
a
Conditional Moderate
a
Because FT4 concentrations below this range are associated with a high risk of fetal hypothyroidism.
* Strength of Recommendation;
#
Level of Evidence; Good Practice Statement.
