Hyperthyroidism
30
Recommendations Table 14. Graves' Disease Preconception
Strength
*
Level
#
e desire for conception should be assessed in women of
childbearing age who have new or existing hyperthyroidism.
Good Practice Statement
e risks and benefits of treatment options for
hyperthyroidism, their impacts on a future pregnancy, and
desired timeline to conception should be discussed in women
with existing hyperthyroidism who are planning pregnancy.
Good Practice Statement
Women taking methimazole (MMI) should be switched to
propylthiouracil (PTU) if they are planning pregnancy.
a
Strong Moderate
a
If PTU is not available or if there are contraindications (allerg y), we recommend that women
continue MMI while trying to conceive, along with a discussion on the pros and cons of stopping
MMI upon a positive pregnancy test and the option to pursue definitive therapy prior to pregnancy.
* Strength of Recommendation;
#
Level of Evidence; Good Practice Statement.
