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Thyroid Disease in Preconception, Pregnancy, and Postpartum

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17 Recommendations Table 7. Thyroid Autoimmunity in Women With Infertility Strength * Level # For euthyroid TPOAb and/or TgAb positive women with infertility, levothyroxine treatment should not be offered. a Strong High For euthyroid TPOAb and/or TgAb positive women planning pregnancy, TSH and FT4 may be rechecked every 3–6 months. Conditional Low For TPOAb and/or TgAb positive women with infertility, do not offer oral prednisolone or intravenous immunoglobulin treatment. Conditional Low a Regardless of TSH concentration or miscarriage history. * Strength of Recommendation; # Level of Evidence; Good Practice Statement. Recommendations Table 8. Subclinical and Overt Hyperthyroidism Preconception Strength * Level # Diagnostic confirmation of subclinical hyperthyroidism in women with infertility should be performed by rechecking TSH and FT4 aer 4–6 weeks. Good Practice Statement Overt hyperthyroidism in women with infertility should be treated preconception, either according to the underlying cause or with a low dose of antithyroid drugs if no underlying cause can be identified. Good Practice Statement * Strength of Recommendation; # Level of Evidence; Good Practice Statement.

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