53
Workup for toxic nodular goiter
or potential other causes
Overt
hyperthyroidism
Taper dosage after
6–12 months to assess
for recovery
Check TPOAb
Initiate
levothyroxine therapy
Retest in 4–8 weeks
Subclinical
hyperthyroidism
Low FT4
Treat if TSH >10 mU/L
Consider treatment if:
1. Symptomatic
2. Planning for pregnancy
3. TPOAb positive
Monitor if treatment is
not elected
Negative
Negative
Normal FT4
High TSH
Green boxes indicate a diagnosis, yellow boxes indicate an action, and orange boxes indicate
recommended follow-up.
