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Thyroid Disease in Preconception, Pregnancy, and Postpartum

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27 Persistently decreased TSH preconception Check FT4 and (F)T3 Overt hyperthyroidism Delay fertility treatment Persistent subclinical hyperthyroidism High FT4 and/or (F)T3 a Ideally the treatment for the etiolog y of hyperthyroidism should be completed and euthyroidism restored (confirmed by 2 TSH concentrations in the reference range at least 6 weeks apart) before fertility treatment begins. b For example if the TSH has been persistently <0.1 mU/L. c Refer to "Subclinical and Overt Hyperthyroidism in Infertility" in Dysfunction and Infertility. Repeat TSH, FT4, and (F)T3 every 4–6 weeks Workup to diagnose and treat Graves' disease, autonomous thyroid nodule(s), or other causes of hyperthyroidism as per the usual evaluation of individuals not considering pregnancy a

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