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Thyroid Disease in Preconception, Pregnancy, and Postpartum

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Hypothyroidism 20 Flowchart 2. Approach to Increased TSH Levels in Pregnancy Start levothyroxine Consider starting levothyroxine Low FT4 TSH <6 mU/L c Consider confirmation test after 1–3 weeks TSH ≥6 mU/L Confirmed overt hypothyroidism Overt hypothyroidism No additional follow-up, unless risk factors (Table 1) Normalized TSH Green boxes indicate a diagnosis, yellow boxes indicate an action, and orange boxes indicate recommended follow-up. a Women with a high TSH have a higher risk of TPOAb positivity. TPOAb positivity can be used for counseling on postpartum thyroiditis and guide screening in future pregnancies. b Or alternatives as described in the thyroid function testing subsection of this guideline.

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