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Thyroid Disease in Preconception, Pregnancy, and Postpartum

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Physiology, Laboratory Testing, and Iodine 2 Figure 1A. Thyroid Physiology During Ovarian Stimulation a Physiologic alterations of serum TSH, FT4, and TBG concentrations are expected from the rise of estrogen during ovarian stimulation. yroxine requirements are extracted from studies of hypothyroid women taking fixed levothyroxine doses. Before ovarian stimulation 4–7 days after ovarian stimulation At time of hCG stimulation 1 week after hCG stimulation 2 weeks after embryo transfer 2 weeks pregnant Thyroxine degradation by D3 a TBG FT4 in patients on fixed LT4 dose TSH in patients on fixed LT4 dose Estrogen TSH FT4

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