5
Medication Classes Associated With Weight Gain
Several classes of medications are associated with weight gain
(see pages 10–11)
• Hormones: Glucocorticoids, growth hormone, insulin
• ß-Blockers: Atenolol, metoprolol, propranolol
• Antidiabetic agents
▶ Thiazolidinediones: Pioglitazone, rosiglitazone
▶ Sulfonylureas: Glipizide, glimepiride, glyburide
▶ Meglitinides: Repaglinide, nateglinide
▶ Insulin
• Anticonvulsants: Gabapentin, pregabalin, divalproex, carbamazepine
• Atypical antipsychotics: Olanzapine, quetiapine
• Antidepressants:
▶ Tricyclic antidepressants (TCAs): Amitriptyline, imipramine
▶ Monoamine oxidase inhibitors (MAOIs): Phenelzine
▶ Selective serotonin reuptake inhibitors (SSRIs): Paroxetine
▶ Atypical antidepressant: Mirtazapine
• Histamine-1 receptor antagonists: Diphenhydramine,
chlorpheniramine, cyproheptadine
Weight-Neutral Medication Classes
• Dipeptidyl peptidase-4 (DPP-4 ) inhibitors: Sitagliptin, saxagliptin,
• linagliptin
• Centrally acting dopamine agonist: Bromocriptine
• α-Glucosidase inhibitors: Acarbose, miglitol, voglibose
• Bile acid sequestrant: Colesevelam
• ß-Blockers: Carvedilol, labetalol, nebivolol
