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AHA/ASA Early Management of Acute Ischemic Stroke 2026

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9 2.5. Role of Mobile Stroke Units COR LOE Recommendations 1 A 1. In patients with suspected AIS, the use of MSUs over conventional EMS where available is recommended for the transport and management of thrombolytic-eligible patients to ensure the fastest achievable onset-to-treatment time and improve functional outcomes. 1 A 2. In patients with suspected acute stroke, MSUs must be equipped to diagnose and treat patients with IVT. 1 B-R 3. In patients with suspected acute stroke, MSU care, including streamlined protocols and use of neurological expertise, either in-person or remote telemedicine consultation, is beneficial for emergent evaluation and treatment of patient symptoms without safety concerns. 2a B-NR 4. In endovascular thrombectomy-eligible patients, use of MSUs can be beneficial to identify and triage patients to the appropriate thrombectomy-capable facility with prehospital notification of receiving stroke teams. 2.6. Hospital Stroke Capabilities COR LOE Recommendation 1 B-NR 1. In hospitals caring for patients with AIS, certification as a stroke specialty hospital certified by an external health care credentialing agency that uses national evidence-based standard criteria is recommended.

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