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AHA/ASA Early Management of Acute Ischemic Stroke 2026

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52 In-Hospital Management of AIS: General Supportive Care 5.6. Other In-Hospital Management Considerations COR LOE Recommendations 2a C-EO 1. For select patients with AIS and their families, referral to palliative care resources is reasonable as appropriate. 3: No benefit A 2. In patients with AIS, routine use of prophylactic antibiotics has not been shown to be beneficial in improving functional outcomes. 3: Harm C-LD 3. In patients with AIS, routine placement of indwelling bladder catheters should not be performed because of the associated risk of catheter-associated urinary tract infections (UTIs). 5.7. Rehabilitation COR LOE Recommendations 1 A 1. In patients with AIS, in-hospital, formal, interdisciplinary assessment and provision of rehabilitation at a level appropriate for the individual patient is recommended to improve functional recovery. 3: No benefit A 2. In patients with AIS, SSRIs are not effective for improving motor recovery or functional status. 3: Harm B-R 3. In patients with AIS, high-dose, very early mobilization within 24 hours of stroke onset is not recommended to improve the odds of a favorable outcome at 3 months and may be harmful.

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