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5.4. Deep Vein Thrombosis Prophylaxis
COR LOE
Recommendations
1 B-R
1. In patients with AIS who have impaired mobility and do
not have contraindications to intermittent pneumatic
compression (IPC), IPC in addition to routine care is
recommended over routine care alone to reduce the risk of
deep vein thrombosis (DVT).
2a B-R
2. In patients with AIS who have impaired mobility, either
prophylactic-dose subcutaneous heparin (UFH or LMWH)
is reasonable to reduce the risk of VTE.
2b A
3. In patients with AIS who have impaired mobility, the
benefit of prophylactic-dose subcutaneous heparin (UFH
or LMWH) over no prophylactic-dose heparin is not well
established to increase overall survival.
2b B-R
4. In patients with AIS who have impaired mobility and who
are selected for prophylactic anticoagulation, the benefit of
prophylactic-dose LMWH over prophylactic-dose UFH to
prevent DVT is uncertain.
3: Harm B-R
5. In patients with AIS who have impaired mobility, elastic
compression stockings cause harm, including skin breakdown,
ulceration, and tissue necrosis, compared with usual care.
5.5. Depression
COR LOE
Recommendations
1 B-NR
1. In patients with AIS, administration of a structured
depression inventory is recommended to routinely screen for
poststroke depression (PSD), although the optimal timing of
screening is uncertain.
1 B-R
2. In patients diagnosed with PSD, treatment with
antidepressants and/or nonpharmacological interventions (ie,
psychotherapy, noninvasive brain stimulation, acupuncture)
is recommended to improve depressive symptoms.
