21
4.3. Blood Pressure Management
COR LOE
Recommendations
Aer Endovascular rombectomy
2a B-NR
9. In patients who undergo EVT, it is reasonable to maintain BP
at a level ≤180/105 mm Hg during and for 24 hours after
the procedure.
3: Harm A
10. (New and of High Impact) In patients with AIS with LVO
of the anterior circulation who have been successfully
recanalized by endovascular therapy (mTICI 2b, 2c, or 3)
and without other indication for blood pressure management
target, intensive SBP reduction target of <140 mm Hg for the
first 72 hours is harmful and not recommended.
4.4. Temperature Management
COR LOE
Recommendations
1 B-R
1. In patients with AIS who have hyperthermia, targeting
normothermia, including using nurse-initiated protocols for
managing fever, is recommended for improving functional
outcomes and reducing death.
1 C-EO
2. In patients with AIS and hyperthermia, sources of
hyperthermia, such as infection, should be identified and
treated to avoid complications.
3: No
benefit
B-R
3. In patients with AIS and normothermia, treatment with
induced hypothermia or prophylactic fever prevention is not
recommended for the purpose of improving outcomes.
4.5. Blood Glucose Management
COR LOE
Recommendations
1 C-LD
1. In patients with AIS, hypoglycemia (blood glucose <60 mg/dL)
should be treated to avoid complications.
2a C-LD
2. In patients with AIS, it is reasonable to treat persistent
hyperglycemia to achieve blood glucose levels in a range of
140 to 180 mg/dL with close monitoring to prevent worse
functional outcomes.
3: No
benefit
A
3. (New and of High Impact) In hospitalized patients with AIS
with hyperglycemia, treatment with IV insulin to achieve
blood glucose levels in the range of 80 to 130 mg/dL is not
recommended to improve 3-month functional outcomes.
(cont'd)
