Tables and Figures
46
Figure 8. DATA Framework for Therapy of Radioactive lodine
Resistant (RAIR) DTC
DATA framework for systemic treatment of patients with RAIR unresectable/metastatic DTC.
a
Initial staging may involve CT, MRI, and/or PET/CT. Consider brain MRI to rule out brain metastases.
b
First imaging and Tg monitoring aer 2–6 months; timing thereaer is based on rate of progression
and/or development of symptoms.
RAIR DTC
Assessment for
Progression
Imaging and
biochemical
staging
a
Comprehensive
somatic genomic
testing
Assess
progression by
serial imaging
and Tg
b
Diagnosis of
RAIR DTC
YES
NO
Symptomatic
and/or large
volume and/or
anatomically
threatening
disease