ASAM Pocket Guidelines and Patient Guide

Benzodiazepine Tapering Patient Guide

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© 2025 American Society of Addiction Medicine. All rights reserved. ASAM.org 16 SPECIAL CONSIDERATIONS If You are Taking Benzodiazepines and Opioids • If you are taking both benzodiazepines and opioids, you may be at increased risk for complications, including overdose. » Consider talking to your healthcare provider about strategies to reduce your risks. • You and your family members should keep opioid overdose reversal medication (e.g., Narcan/naloxone) on hand. • Naloxone can reverse an opioid overdose. It is available with a healthcare provider's prescription or without a prescription for purchase at many local pharmacies. Naloxone may also be distributed for free by community groups or your local health department. If You Have or May Have a Substance Use Disorder • You may have a substance use disorder if: » You are continuing to take a substance despite its negative impact on your health, job, or relationships. » You are taking prescription medication more frequently or in larger doses than prescribed. » You are taking prescription medication to feel pleasure or enjoyment. » You would like to stop or reduce substance use but find that you can't (e.g., because of cravings). » You're considering buying pills from the internet or a dealer. Pills purchased outside a pharmacy can contain fentanyl and put you at risk for overdose and death. • Talk with your healthcare provider if you're concerned about your substance use. They may assess you for a substance use disorder or refer you to another healthcare provider for assessment. • If you have a substance use disorder: » Your healthcare provider may assess the risks and benefits of continued benzodiazepine use more frequently. » You should receive treatment for the underlying substance use disorder while you are tapering the benzodiazepine. » Your healthcare provider should coordinate care with a substance use disorder treatment provider.

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