ATS GUIDELINES Bundle

Children With Progressive Pulmonary Hypertension Despite Optimal Therapy

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Issue link: https://eguideline.guidelinecentral.com/i/1531118

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Treatment Recommendation 1 ➤ We suggest ASD-intervention for children with progressive PH and right ventricular (RV) failure despite optimal therapy (conditional recommendation, very low certainty of evidence). Recommendation 2 ➤ We suggest creation of a pulmonary-to-systemic shunt in children with progressive PH and suprasystemic RV pressure despite optimal therapy (conditional recommendation, very low certainty of evidence). Recommendation 3 ➤ We suggest lung transplantation in children with progressive PH and RV failure despite optimal therapy (conditional recommendation, very low certainty of evidence). Recommendation 4 ➤ We suggest lung transplantation in children with progressive PH and RV failure despite optimal therapy who are on extracorporeal membrane oxygenation (ECMO) support without reversible cause (conditional recommendation, very low certainty of evidence). Recommendation 5 ➤ We suggest against pulmonary-to-systemic shunt creation for children with progressive PH and suprasystemic RV pressure despite optimal therapy who are on ECMO support without reversible cause (conditional recommendation, very low certainty of evidence).

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