Table
4.
Examples
of
Antimicrobial
Locks
Antimicrobial Lock
Therapy
Vial
Concentration
Vol.
1
mL
Vol.
2
mL
Vol.
3
mL
Vol.
5
mL
Final Concentration
Stability
Vancomycin
Vancomycin,
50
mg/mL
vial
0.2
0.4
0.6
1.0
10
mg/mL
7
days
refrigerated
0.9%
normal
saline
(NS)
0.8
1.6
2.4
4.4
Vancomycin,
5
mg/mL
solution
(dilute
with
NS)
0.5
1.0
1.5
2.5
2.5
mg/mL
Heparin,
100
units/mL
0.5
1.0
1.5
2.5
50
units/mL
Gentamicin
Gentamicin,
10
mg/mL
vial
0.5
1.0
1.5
2.5
5
mg/mL
7
days
refrigerated
0.9%
NS
0.5
1.0
1.5
2.5
Ceazidime
Ceftazidime,
100
mg/mL
vial
0.1
0.2
0.3
0.5
10
mg/mL
7
days
refrigerated
Heparin,
100
units/mL
0.5
1.0
1.5
2.5
50
units/mL
0.9%
NS
0.4
0.8
1.2
2.0
—
Amphotericin
B
a
Amphotericin
B,
5
mg/mL
vial
0.5
1.0
1.5
2.5
2.5
mg/mL
7
days
refrigerated
Heparin,
100
units/mL
0.5
1.0
1.5
2.5
50
units/mL
a
Rarely
used
since
removal
of
catheter
is
recommended
in
the
setting
of
fungemia.
Management
